Anti-TMEM98 antibody (STJA0007331)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TMEM98
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protein 98 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMEM98 |
| Gene ID | 26022 |
| Uniprot ID | TMM98_HUMAN |
| Immunogen | Synthesized peptide derived from human TMEM98 |
| Specificity | This antibody detects endogenous levels of TMEM98 at Human, Mouse, Rat |
Additional Info
| Function | Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1). |
| Protein Name | Transmembrane Protein 98Protein Tada1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinSecretedExtracellular ExosomeEndoplasmic Reticulum MembraneSecreted By Exosomes Through A Non-Classical Pathway |
| Alternative Antibody Names | Anti-Transmembrane Protein 98 antibodyAnti-Protein Tada1 antibodyAnti-TMEM98 antibodyAnti-UNQ536 antibodyAnti-PRO1079 antibody |
Information sourced from Uniprot.org