Anti-TMEM55A antibody (130-195) (STJ117666)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TMEM55A (130-195) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PIP4P2 |
| Gene ID | 55529 |
| Uniprot ID | PP4P2_HUMAN |
| Immunogen Region | 130-195 |
| Immunogen Sequence | VMLISEEQPAQPALPIQPEG TRVVCGHCGNTFLWMELRFN TLAKCPHCKKISSVGSALPR RRCCAY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 130-195 of human TMEM55A (NP_061180.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. Negatively regulates the phagocytosis of large particles by reducing phagosomal phosphatidylinositol 4,5-bisphosphate accumulation during cup formation. |
| Protein Name | Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-PhosphataseType 2 Ptdins-4 -5-P2 4-PtasePtdins-4 -5-P2 4-Ptase IiTransmembrane Protein 55a |
| Database Links | |
| Cellular Localisation | Late Endosome MembraneMulti-Pass Membrane ProteinLysosome MembraneCytoplasmic VesiclePhagosome MembraneCell Membrane |
| Alternative Antibody Names | Anti-Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-Phosphatase antibodyAnti-Type 2 Ptdins-4 -5-P2 4-Ptase antibodyAnti-Ptdins-4 -5-P2 4-Ptase Ii antibodyAnti-Transmembrane Protein 55a antibodyAnti-PIP4P2 antibodyAnti-TMEM55A antibody |
Information sourced from Uniprot.org