Anti-TMEM266 antibody (STJA0008947)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C15orf27
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protein 266 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMEM266 |
| Gene ID | 123591 |
| Uniprot ID | TM266_HUMAN |
| Immunogen | Synthesized peptide derived from human C15orf27 |
| Specificity | This antibody detects endogenous levels of C15orf27 at Human, Mouse |
Additional Info
| Function | Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear. Undergoes both rapid and slow structural rearrangements in response to changes in voltage. Contains a zinc-binding site that can regulate the slow conformational transition. |
| Protein Name | Transmembrane Protein 266Htmem266Hv1-Related Protein 1Hshvrp1 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonPresent In The Dendrites And Soma Of Cerebellar Granule NeuronsBut Not In Their Axon |
| Alternative Antibody Names | Anti-Transmembrane Protein 266 antibodyAnti-Htmem266 antibodyAnti-Hv1-Related Protein 1 antibodyAnti-Hshvrp1 antibodyAnti-TMEM266 antibodyAnti-C15orf27 antibodyAnti-HVRP1 antibody |
Information sourced from Uniprot.org