Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-TMEFF2 antibody (STJ192092)

SKU:
STJ192092
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Tomoregulin-2 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TMEFF2
Gene ID: 23671
Uniprot ID: TEFF2_HUMAN
Specificity: TEFF2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications O-glycosylated.contains chondroitin sulfate glycosaminoglycans. A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
Protein Name Tomoregulin-2
Tr-2
Hyperplastic Polyposis Protein 1
Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains
Cellular Localisation Isoform 1: Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Membrane
Isoform 3: Secreted
Alternative Antibody Names Anti-Tomoregulin-2 antibody
Anti-Tr-2 antibody
Anti-Hyperplastic Polyposis Protein 1 antibody
Anti-Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains antibody
Anti-TMEFF2 antibody
Anti-HPP1 antibody
Anti-TENB2 antibody
Anti-TPEF antibody
Anti-UNQ178 antibody
Anti-PRO204 antibody

Information sourced from Uniprot.org

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