Anti-TMEFF2 antibody [SAA1493] (STJA0019921)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Tomoregulin-2 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1493 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | TMEFF2 |
| Gene ID | 23671 |
| Uniprot ID | TEFF2_HUMAN |
Additional Info
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate glycosaminoglycans. A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17. |
| Function | May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. |
| Protein Name | Tomoregulin-2Tr-2Hyperplastic Polyposis Protein 1Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains |
| Database Links | |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: MembraneIsoform 3: Secreted |
| Alternative Antibody Names | Anti-Tomoregulin-2 antibodyAnti-Tr-2 antibodyAnti-Hyperplastic Polyposis Protein 1 antibodyAnti-Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains antibodyAnti-TMEFF2 antibodyAnti-HPP1 antibodyAnti-TENB2 antibodyAnti-TPEF antibodyAnti-UNQ178 antibodyAnti-PRO204 antibody |
Information sourced from Uniprot.org