Anti-TMEFF1 antibody [30C10] (STJA0027759)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal Tomoregulin-1 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 30C10 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1.66 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TMEFF1 |
| Gene ID | 100526694/8577 |
| Uniprot ID | TEFF1_HUMAN |
Additional Info
| Function | Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers. |
| Protein Name | Tomoregulin-1Tr-1H7365Transmembrane Protein With Egf-Like And One Follistatin-Like Domain |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tomoregulin-1 antibodyAnti-Tr-1 antibodyAnti-H7365 antibodyAnti-Transmembrane Protein With Egf-Like And One Follistatin-Like Domain antibodyAnti-TMEFF1 antibodyAnti-C9orf2 antibody |
Information sourced from Uniprot.org