| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Bax inhibitor 1 (93-143) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMBIM6 |
| Gene ID: | 7009 |
| Uniprot ID: | BI1_HUMAN |
| Immunogen Region: | 93-143 |
| Specificity: | This antibody detects endogenous levels of human BI1 |
| Immunogen: | Synthesized peptide derived from human BI1 AA range: 93-143 |
| Function | Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. |
| Protein Name | Bax Inhibitor 1Bi-1Testis-Enhanced Gene Transcript ProteinTransmembrane Bax Inhibitor Motif-Containing Protein 6 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Bax Inhibitor 1 antibodyAnti-Bi-1 antibodyAnti-Testis-Enhanced Gene Transcript Protein antibodyAnti-Transmembrane Bax Inhibitor Motif-Containing Protein 6 antibodyAnti-TMBIM6 antibodyAnti-BI1 antibodyAnti-TEGT antibody |
Information sourced from Uniprot.org