Anti-TM7SF2 antibody (160-250) (STJ119631)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TM7SF2 (160-250) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TM7SF2 |
| Gene ID | 7108 |
| Uniprot ID | ERG24_HUMAN |
| Immunogen Region | 160-250 |
| Immunogen Sequence | LAPGGNSGNPIYDFFLGREL NPRICFFDFKYFCELRPGLI GWVLINLALLMKEAELRGSP SLAMWLVNGFQLLYVGDALW HEEAVLTTMDI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 160-250 of human TM7SF2 (NP_003264.2). |
Additional Info
| Tissue Specificity | Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. |
| Function | Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. |
| Protein Name | Delta(14-Sterol Reductase Tm7sf2Delta-14-Sr3-Beta-Hydroxysterol Delta14-ReductaseAnother New Gene 1 ProteinC-14 Sterol ReductaseC14srPutative Sterol Reductase Sr-1Sterol C14-ReductaseTransmembrane 7 Superfamily Member 2 |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Delta(14-Sterol Reductase Tm7sf2 antibodyAnti-Delta-14-Sr antibodyAnti-3-Beta-Hydroxysterol Delta antibodyAnti-14-Reductase antibodyAnti-Another New Gene 1 Protein antibodyAnti-C-14 Sterol Reductase antibodyAnti-C14sr antibodyAnti-Putative Sterol Reductase Sr-1 antibodyAnti-Sterol C14-Reductase antibodyAnti-Transmembrane 7 Superfamily Member 2 antibodyAnti-TM7SF2 antibodyAnti-ANG1 antibody |
Information sourced from Uniprot.org