Anti-TLR4/MD2 antibody [MTS510] (STJ16100494)

SKU:
STJ16100494-1

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Host: Rat
Applications: IHC-F/FC/IF/IP
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rat monoclonal antibody anti-TLR4/MD2 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunofluorescence and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: MTS510
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Concentration: 100 ug/mL
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: LY96
Gene ID: 23643
Uniprot ID: LY96_HUMAN
Post Translational Modifications N-glycosylated.high-mannose.
Function Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS.
Protein Name Lymphocyte Antigen 96
Ly-96
Esop-1
Protein Md-2
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-140534
Reactome: R-HSA-166016
Reactome: R-HSA-166058
Reactome: R-HSA-166166
Reactome: R-HSA-2562578
Reactome: R-HSA-5602498
Reactome: R-HSA-5603041
Reactome: R-HSA-5686938
Reactome: R-HSA-936964
Reactome: R-HSA-937041
Reactome: R-HSA-937072
Reactome: R-HSA-9707616
Reactome: R-HSA-975163
Cellular Localisation Secreted
Extracellular Space
Retained In The Extracellular Space At The Cell Surface By Interaction With Tlr4
Alternative Antibody Names Anti-Lymphocyte Antigen 96 antibody
Anti-Ly-96 antibody
Anti-Esop-1 antibody
Anti-Protein Md-2 antibody
Anti-LY96 antibody
Anti-ESOP1 antibody
Anti-MD2 antibody

Information sourced from Uniprot.org

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