| Host: | Rabbit |
| Applications: | ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Chimpanzee/Human/Monkey/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TLR10 (380-430) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.67 µg/µl |
| Dilution Range: | WB: 1:500 ELISA: 1:20, 000 IP: 1:200 IHC: 1:100 ICC: 1:100 IF: 1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | TLR10 |
| Gene ID: | 81793 |
| Uniprot ID: | TLR10_HUMAN |
| Immunogen Region: | 380-430 |
| Immunogen: | Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein. |
| Tissue Specificity | Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| Protein Name | Toll-Like Receptor 10 Cd Antigen Cd290 |
| Database Links | Reactome: R-HSA-168142 Reactome: R-HSA-5603037 Reactome: R-HSA-975871 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Toll-Like Receptor 10 antibody Anti-Cd Antigen Cd290 antibody Anti-TLR10 antibody Anti-UNQ315 antibody Anti-PRO358 antibody |
Information sourced from Uniprot.org