Anti-TLE5 antibody (STJ192150)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-TLE family member 5 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TLE5 |
| Gene ID | 166 |
| Uniprot ID | TLE5_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | AES Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Ubiquitinated by XIAP/BIRC4. |
| Function | Transcriptional corepressor. Acts as a dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. |
| Protein Name | Tle Family Member 5Amino-Terminal Enhancer Of SplitAmino Enhancer Of SplitGp130-Associated Protein GamGrg-5Groucho-Related Protein 5Protein Esp1Protein GrgTle Family Member 5 - Transcriptional Modulator |
| Database Links | Reactome: R-HSA-4641265 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Tle Family Member 5 antibodyAnti-Amino-Terminal Enhancer Of Split antibodyAnti-Amino Enhancer Of Split antibodyAnti-Gp130-Associated Protein Gam antibodyAnti-Grg-5 antibodyAnti-Groucho-Related Protein 5 antibodyAnti-Protein Esp1 antibodyAnti-Protein Grg antibodyAnti-Tle Family Member 5 - Transcriptional Modulator antibodyAnti-TLE5 antibodyAnti-AES antibodyAnti-GRG antibodyAnti-GRG5 antibody |
Information sourced from Uniprot.org