Anti-TK1 nanobody [SAA1373] (STJN000094)

Name: Anti-TK1 nanobody [SAA1373] (STJN000094)
SKU: STJN000094
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostAlpaca

ConjugationUnconjugated

IsotypeVHH-8His-Cys-tag

STJN000094

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Short Description	Alpaca monoclonal nanobody anti-Thymidine Kinase-Cytosolic is suitable for use in Dot Blot, ELISA, Flow Cytometry and Western Blot research applications.
Applications	DB/ELISA/FC/WB
Host	Alpaca
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	SAA1373
Isotype	VHH-8His-Cys-tag
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	Purified by Nickel column.
Formulation	0.01M PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Function	Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT).
Protein Name	Thymidine Kinase - Cytosolic
Database Links	Reactome: R-HSA-69205 Reactome: R-HSA-73614
Cellular Localisation	Cytoplasm
Alternative Nanobody Names	Anti-Thymidine Kinase - Cytosolic nanobody Anti-TK1 nanobody

Information sourced from Uniprot.org