• Immunohistochemistry of rat Ovary with Anti-TIPIN primary antibody (STJ503263) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-TIPIN antibody (240-270) (STJ503263)

SKU:
STJ503263-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TIPIN (240-270) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.96-0.98 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: TIPIN
Gene ID: 54962
Uniprot ID: TIPIN_HUMAN
Immunogen Region: 240-270
Immunogen: Synthetic peptide taken within amino acid region 240-270 on mouse TIPIN protein.
Function Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.
Protein Name Timeless-Interacting Protein
Database Links Reactome: R-HSA-5693607
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Timeless-Interacting Protein antibody
Anti-TIPIN antibody

Information sourced from Uniprot.org

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