Anti-TINAG antibody (80-130 aa) (STJ196088)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TINAG at the amino acid range 80-130
General Information
| Short Description | Rabbit polyclonal anti-Tubulointerstitial nephritis antigen (80-130 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TINAG |
| Gene ID | 27283 |
| Uniprot ID | TINAG_HUMAN |
| Immunogen | Synthesized peptide derived from the human TINAG at the amino acid range 80-130 |
| Immunogen Region | 80-130 aa |
| Specificity | This antibody detects endogenous levels of TINAG at Human |
Additional Info
| Post Translational Modifications | It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus 2 alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
| Function | Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein. |
| Protein Name | Tubulointerstitial Nephritis AntigenTin-Ag |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Tubulointerstitial Nephritis Antigen antibodyAnti-Tin-Ag antibodyAnti-TINAG antibody |
Information sourced from Uniprot.org