Anti-TIMM50 antibody (1-100) [S6MR] (STJ11101436)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal TIMM50 (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM50 |
| Gene ID | 92609 |
| Uniprot ID | TIM50_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MAASAAVFSRLRSGLRLGSR GLCTRLATPPRRAPDQAAEI GSRGSTKAQGPQQQPGSEGP SYAKKVALWLAGLLGAGGTV SVVYIFGNNPVDENGAKIPD |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TIMM50 (Q3ZCQ8). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level). |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro.however such activity may not be relevant in vivo. Isoform 2: May participate in the release of snRNPs and SMN from the Cajal body. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim50 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinIsoform 2: Nucleus SpeckleNuclear And Enriched In Speckles With Snrnps |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim50 antibodyAnti-TIMM50 antibodyAnti-TIM50 antibodyAnti-PRO1512 antibody |
Information sourced from Uniprot.org