Anti-TIMM44 antibody (153-452) (STJ119562)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMM44 (153-452) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM44 |
| Gene ID | 10469 |
| Uniprot ID | TIM44_HUMAN |
| Immunogen Region | 153-452 |
| Immunogen Sequence | AKTAKQSAESVSKGGEKLGR TAAFRALSQGVESVKKEIDD SVLGQTGPYRRPQRLRKRTE FAGDKFKEEKVFEPNEEALG VVLHKDSKWYQQWKDFKENN VVFNRFFEMKMKYDESDNAF IRASRALTDKVTDLLGGLFS KTEMSEVLTEILRVDPAFDK DRFLKQCENDIIPNVLEAMI SGELDILKDWCYEATYSQLA HPIQQAKALGLQFHSRILDI DNVDLAMGKMMEQGPVLII |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2). |
Additional Info
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim44 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideMitochondrion Matrix |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim44 antibodyAnti-TIMM44 antibodyAnti-MIMT44 antibodyAnti-TIM44 antibody |
Information sourced from Uniprot.org