Anti-TIMM22 antibody [R47-2K-6] (STJA0035631)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TIMM22
General Information
| Short Description | Rabbit monoclonal anti-TIMM22 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R47-2K-6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TIMM22 |
| Gene ID | 29928 |
| Uniprot ID | TIM22_HUMAN |
| Immunogen | A synthesized peptide derived from human TIMM22 |
Additional Info
| Post Translational Modifications | Disulfide bonds promote efficient assembly of the TIM22 complex. |
| Function | Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim22Testis-Expressed Protein 4 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim22 antibodyAnti-Testis-Expressed Protein 4 antibodyAnti-TIMM22 antibodyAnti-TEX4 antibodyAnti-TIM22 antibody |
Information sourced from Uniprot.org