Anti-TIMM13 antibody (1-95 aa) (STJ11106948)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMM13 (1-95 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM13 |
| Gene ID | 26517 |
| Uniprot ID | TIM13_HUMAN |
| Immunogen Region | 1-95 aa |
| Immunogen Sequence | MEGGFGSDFGGSGSGKLDPG LIMEQVKVQIAVANAQELLQ RMTDKCFRKCIGKPGGSLDN SEQKCIAMCMDRYMDAWNTV SRAYNSRLQRERANM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human TIMM13 ( NP_036590.1 ). |
Additional Info
| Tissue Specificity | Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. |
| Function | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim13 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane Side |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim13 antibodyAnti-TIMM13 antibodyAnti-TIM13B antibodyAnti-TIMM13A antibodyAnti-TIMM13B antibody |
Information sourced from Uniprot.org