Anti-TIM50 antibody (Internal) (STJ70601)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TIM50 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 39kDa in Human Heart lysate (Calculated MW of 50.5kDa according to NP_001001563.1). The observed molecular weight corresponds to earlier finding in literature with different an |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM50 |
| Gene ID | 92609 |
| Uniprot ID | TIM50_HUMAN |
| Accession Number | NP_001001563.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | CDVRTVLEHYALEDD |
| Specificity | This antibody is expected to recognise an epitope corresponding to aa 396-409 of human TIM50. |
Additional Info
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro.however such activity may not be relevant in vivo. Isoform 2: May participate in the release of snRNPs and SMN from the Cajal body. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim50 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinIsoform 2: Nucleus SpeckleNuclear And Enriched In Speckles With Snrnps |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim50 antibodyAnti-TIMM50 antibodyAnti-TIM50 antibodyAnti-PRO1512 antibody |
Information sourced from Uniprot.org