| Short Description : | Rabbit polyclonal anti-Tyrosine-protein kinase receptor Tie-1 (851-900 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 100-300WB 1:500-1:2000ELISA 1:10000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIE1 |
| Gene ID: | 7075 |
| Uniprot ID: | TIE1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TIE1 at the amino acid range 851-900 |
| Immunogen Region: | 851-900 aa |
| Specificity: | Tie-1 Polyclonal Antibody detects endogenous levels of Tie-1 protein. |
| Post Translational Modifications | Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. |
| Function | Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
| Protein Name | Tyrosine-Protein Kinase Receptor Tie-1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Receptor Tie-1 antibodyAnti-TIE1 antibodyAnti-TIE antibody |
Information sourced from Uniprot.org
