Host: |
Rabbit |
Applications: |
ELISA/WB |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TICRR is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.55-0.75 µg/µl |
Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
TICRR |
Gene ID: |
90381 |
Uniprot ID: |
TICRR_HUMAN |
Immunogen: |
Synthetic peptide corresponding to unique amino acid sequence on human Treslin protein. |
Function | Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. |
Protein Name | TreslinTopbp1-Interacting Checkpoint And Replication RegulatorTopbp1-Interacting - Replication-Stimulating Protein |
Cellular Localisation | NucleusAssociates With Chromatin |
Alternative Antibody Names | Anti-Treslin antibodyAnti-Topbp1-Interacting Checkpoint And Replication Regulator antibodyAnti-Topbp1-Interacting - Replication-Stimulating Protein antibodyAnti-TICRR antibodyAnti-C15orf42 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance