Anti-Thyroid Peroxidase antibody [R08-6C2] (STJA0036662)

SKU:
STJA0036662
€160.20 - €337.80
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Short Description :Rabbit monoclonal anti-Thyroid Peroxidase for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/IP
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R08-6C2
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IP 1:40
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:TPO
Gene ID:7173
Uniprot ID:PERT_HUMAN
Immunogen:A synthesized peptide derived from human TPO
Post Translational Modifications Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part.
Function Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
Protein Name Thyroid Peroxidase
Tpo
Database Links Reactome: R-HSA-209968
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-Thyroid Peroxidase antibody
Anti-Tpo antibody
Anti-TPO antibody

Information sourced from Uniprot.org