Anti-Thymidylate Synthase antibody [ZN227] (STJA0033389)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenFull length human recombinant protein of human TYMS (TS) (NP_001062) produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Thymidylate Synthase for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN227 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TYMS |
| Gene ID | 7298 |
| Uniprot ID | TYSY_HUMAN |
| Immunogen | Full length human recombinant protein of human TYMS (TS) (NP_001062) produced in E.coli. |
Additional Info
| Function | Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Protein Name | Thymidylate SynthaseTsTsase |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmMitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Thymidylate Synthase antibodyAnti-Ts antibodyAnti-Tsase antibodyAnti-TYMS antibodyAnti-TS antibodyAnti-OK antibodyAnti-SW-cl.29 antibody |
Information sourced from Uniprot.org