Anti-THRSP antibody (1-146) (STJ29312)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal THRSP (1-146) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | THRSP |
| Gene ID | 7069 |
| Uniprot ID | THRSP_HUMAN |
| Immunogen Region | 1-146 |
| Immunogen Sequence | MQVLTKRYPKNCLLTVMDRY AAEVHNMEQVVMIPSLLRDV QLSGPGGQAQAEAPDLYTYF TMLKAICVDVDHGLLPREEW QAKVAGSEENGTAETEEVED ESASGELDLEAQFHLHFSSL HHILMHLTEKAQEVTRKYQE MTGQVW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human THRSP (NP_003242.1). |
Additional Info
| Tissue Specificity | Mainly expressed in tissues that synthesize triglycerides. |
| Function | Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. |
| Protein Name | Thyroid Hormone-Inducible Hepatic ProteinSpot 14 ProteinS14Spot14 |
| Database Links | Reactome: R-HSA-200425Reactome: R-HSA-9841922 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Thyroid Hormone-Inducible Hepatic Protein antibodyAnti-Spot 14 Protein antibodyAnti-S14 antibodyAnti-Spot14 antibodyAnti-THRSP antibody |
Information sourced from Uniprot.org