Thromboxane A Synthase antibody western blot human fetal liver STJA0037273

Anti-Thromboxane A Synthase antibody [R06-8C5] (STJA0037273)

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STJA0037273
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-Thromboxane A Synthase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R06-8C5
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:TBXAS1
Gene ID:6916
Uniprot ID:THAS_HUMAN
Immunogen:A synthesized peptide derived from human Thromboxane synthase
Tissue Specificity Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
Function Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
Protein Name Thromboxane-A Synthase
Txa Synthase
Txs
Cytochrome P450 5a1
Hydroperoxy Icosatetraenoate Dehydratase
Database Links Reactome: R-HSA-211979
Reactome: R-HSA-2162123
Reactome: R-HSA-5579032
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Thromboxane-A Synthase antibody
Anti-Txa Synthase antibody
Anti-Txs antibody
Anti-Cytochrome P450 5a1 antibody
Anti-Hydroperoxy Icosatetraenoate Dehydratase antibody
Anti-TBXAS1 antibody
Anti-CYP5 antibody
Anti-CYP5A1 antibody
Anti-TXAS antibody

Information sourced from Uniprot.org

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