| Short Description : | Rabbit polyclonal THRB (1-263) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:2000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | THRB |
| Gene ID: | 7068 |
| Uniprot ID: | THB_HUMAN |
| Immunogen Region: | 1-263 |
| Immunogen Sequence: | MTPNSMTENGLTAWDKPKHC PDREHDWKLVGMSEACLHRK SHSERRSTLKNEQSSPHLIQ TTWTSSIFHLDHDDVNDQSV SSAQTFQTEEKKCKGYIPSY LDKDELCVVCGDKATGYHYR CITCEGCKGFFRRTIQKNLH PSYSCKYEGKCVIDKVTRNQ CQECRFKKCIYVGMATDLVL DDSKRLAKRKLIEENREKRR REELQKSIGHKPEPTDEEWE LIKTVTEAHVATNAQGSHW |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human TR Beta 1/THRB (NP_000452.2). |
| Function | Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. |
| Protein Name | Thyroid Hormone Receptor BetaNuclear Receptor Subfamily 1 Group A Member 2C-Erba-2C-Erba-Beta |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-4090294 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Thyroid Hormone Receptor Beta antibodyAnti-Nuclear Receptor Subfamily 1 Group A Member 2 antibodyAnti-C-Erba-2 antibodyAnti-C-Erba-Beta antibodyAnti-THRB antibodyAnti-ERBA2 antibodyAnti-NR1A2 antibodyAnti-THR1 antibody |
Information sourced from Uniprot.org
