Anti-Thioredoxin Reductase 2 antibody [R02-2D6] (STJA0034968)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human TXNRD2
General Information
| Short Description | Rabbit monoclonal anti-Thioredoxin Reductase 2 for use in WB and IHC-P in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-2D6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TXNRD2 |
| Gene ID | 10587 |
| Uniprot ID | TRXR2_HUMAN |
| Immunogen | A synthetic peptide of human TXNRD2 |
Additional Info
| Tissue Specificity | Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. high levels in kidney, whereas levels are low. High expression is observed in the adrenal cortex. |
| Function | Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. |
| Protein Name | Thioredoxin Reductase 2 - MitochondrialSelenoprotein ZSelzTr-BetaThioredoxin Reductase Tr3 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Thioredoxin Reductase 2 - Mitochondrial antibodyAnti-Selenoprotein Z antibodyAnti-Selz antibodyAnti-Tr-Beta antibodyAnti-Thioredoxin Reductase Tr3 antibodyAnti-TXNRD2 antibodyAnti-KIAA1652 antibodyAnti-TRXR2 antibody |
Information sourced from Uniprot.org