Anti-Thimet Oligopeptidase antibody [2D3] (STJA0032724)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenFull length human recombinant protein of human THOP1 produced in 293T cell.
General Information
| Short Description | Mouse monoclonal anti-Thimet Oligopeptidase for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2D3 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 0.67 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | THOP1 |
| Gene ID | 7064 |
| Uniprot ID | THOP1_HUMAN |
| Immunogen | Full length human recombinant protein of human THOP1 produced in 293T cell. |
Additional Info
| Function | Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1. |
| Protein Name | Thimet OligopeptidaseEndopeptidase 24.15Mp78 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Thimet Oligopeptidase antibodyAnti-Endopeptidase 24.15 antibodyAnti-Mp78 antibodyAnti-THOP1 antibody |
Information sourced from Uniprot.org