Anti-TGN46/TGOLN2 antibody (1-100) [S6MR] (STJ11103056)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal TGN46/TGOLN2 (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000IHC-P:1:100-1:1000IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TGOLN2 |
| Gene ID | 10618 |
| Uniprot ID | TGON2_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MRFVVALVLLNVAAAGAVPL LATESVKQEEAGVRPSAGNV STHPSLSQRPGGSTKSHPEP QTPKDSPSKSSAEAQTPEDT PNKSGAEAKTQKDSSNKSGA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TGN46/TGOLN2 (O43493). |
Additional Info
| Tissue Specificity | Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. |
| Function | May be involved in regulating membrane traffic to and from trans-Golgi network. |
| Protein Name | Trans-Golgi Network Integral Membrane Protein 2Trans-Golgi Network Glycoprotein 46Tgn38 HomologHtgn46Trans-Golgi Network Glycoprotein 48Htgn48Trans-Golgi Network Glycoprotein 51Htgn51Trans-Golgi Network Protein 2 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-432722Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinGolgi ApparatusTrans-Golgi Network MembranePrimarily In Trans-Golgi NetworkCycles Between The Trans-Golgi Network And The Cell Surface Returning Via Endosomes |
| Alternative Antibody Names | Anti-Trans-Golgi Network Integral Membrane Protein 2 antibodyAnti-Trans-Golgi Network Glycoprotein 46 antibodyAnti-Tgn38 Homolog antibodyAnti-Htgn46 antibodyAnti-Trans-Golgi Network Glycoprotein 48 antibodyAnti-Htgn48 antibodyAnti-Trans-Golgi Network Glycoprotein 51 antibodyAnti-Htgn51 antibodyAnti-Trans-Golgi Network Protein 2 antibodyAnti-TGOLN2 antibodyAnti-TGN46 antibodyAnti-TGN51 antibody |
Information sourced from Uniprot.org