Anti-TGIF2 antibody (Internal) (STJ70768)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TGIF2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 22kDa band observed in lysates of A431, A549 and HEK293 cell lines (calculated MW of 25.9kDa according to NP_068581.1). Recommended concentration: 0.3-1.0µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TGIF2 |
| Gene ID | 60436 |
| Uniprot ID | TGIF2_HUMAN |
| Accession Number | NP_068581.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | EMELQKQQDP |
Additional Info
| Post Translational Modifications | The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. |
| Function | Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. |
| Protein Name | Homeobox Protein Tgif25'-Tg-3'-Interacting Factor 2Tgf-Beta-Induced Transcription Factor 2Tgfb-Induced Factor 2 |
| Database Links | Reactome: R-HSA-2173795Reactome: R-HSA-2173796 |
| Cellular Localisation | NucleusExcluded From Nucleoli |
| Alternative Antibody Names | Anti-Homeobox Protein Tgif2 antibodyAnti-5'-Tg-3'-Interacting Factor 2 antibodyAnti-Tgf-Beta-Induced Transcription Factor 2 antibodyAnti-Tgfb-Induced Factor 2 antibodyAnti-TGIF2 antibody |
Information sourced from Uniprot.org