Anti-TFPI antibody [SAA2013] (STJA0020560)

SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationUnconjugated
IsotypeIgG4
STJA0020560
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General Information

Short DescriptionHuman monoclonal Tissue Factor Pathway Inhibitor antibody for use in ELISA, FC and WB in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/FC/WB
HostHuman
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS

Product Properties

ClonalityMonoclonal
Clone IDSAA2013
IsotypeIgG4
ConjugationUnconjugated
Concentration1 mg/mL
PurificationProtein A/G purified from cell culture supernatant
Formulation0.01M PBS, pH 7.4.
Storage InstructionSuitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months

Target Information

Gene SymbolTFPI
Gene ID7035
Uniprot IDTFPI1_HUMAN

Additional Info

Post Translational Modifications O-glycosylated.
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Protein Name Tissue Factor Pathway Inhibitor
Tfpi
Extrinsic Pathway Inhibitor
Epi
Lipoprotein-Associated Coagulation Inhibitor
Laci
Database Links Reactome: R-HSA-140834
Cellular Localisation Isoform Alpha: Secreted
Isoform Beta: Microsome Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Tissue Factor Pathway Inhibitor antibody
Anti-Tfpi antibody
Anti-Extrinsic Pathway Inhibitor antibody
Anti-Epi antibody
Anti-Lipoprotein-Associated Coagulation Inhibitor antibody
Anti-Laci antibody
Anti-TFPI antibody
Anti-LACI antibody
Anti-TFPI1 antibody

Information sourced from Uniprot.org

Citations

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