Anti-TFPI antibody (251-300 aa) (STJ96600)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human TFPI at the amino acid range 251-300
General Information
| Short Description | Rabbit polyclonal anti-Tissue factor pathway inhibitor (251-300 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TFPI |
| Gene ID | 7035 |
| Uniprot ID | TFPI1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human TFPI at the amino acid range 251-300 |
| Immunogen Region | 251-300 aa |
| Specificity | TFPI Polyclonal Antibody detects endogenous levels of TFPI protein. |
Additional Info
| Post Translational Modifications | O-glycosylated. |
| Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
| Protein Name | Tissue Factor Pathway InhibitorTfpiExtrinsic Pathway InhibitorEpiLipoprotein-Associated Coagulation InhibitorLaci |
| Database Links | Reactome: R-HSA-140834 |
| Cellular Localisation | Isoform Alpha: SecretedIsoform Beta: Microsome MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Tissue Factor Pathway Inhibitor antibodyAnti-Tfpi antibodyAnti-Extrinsic Pathway Inhibitor antibodyAnti-Epi antibodyAnti-Lipoprotein-Associated Coagulation Inhibitor antibodyAnti-Laci antibodyAnti-TFPI antibodyAnti-LACI antibodyAnti-TFPI1 antibody |
Information sourced from Uniprot.org