• Western blot analysis of extracts of BxPC-3 cells, using TFPI rabbit monoclonal antibody (STJ11102359) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of extracts of BxPC-3 cells, using TFPI Rabbit monoclonal antibody (STJ11102359) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TFPI antibody (200-304) [S9MR] (STJ11102359)

SKU:
STJ11102359

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-TFPI (200-304) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S9MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TFPI
Gene ID: 7035
Uniprot ID: TFPI1_HUMAN
Immunogen Region: 200-304
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-304 of human TFPI (P10646).
Immunogen Sequence: PQSTKVPSLFEFHGPSWCLT PADRGLCRANENRFYYNSVI GKCRPFKYSGCGGNENNFTS KQECLRACKKGFIQRISKGG LIKTKRKRKKQRVKIAYEEI FVKNM
Tissue Specificity Mostly in endothelial cells.
Post Translational Modifications O-glycosylated.
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Protein Name Tissue Factor Pathway Inhibitor
Tfpi
Extrinsic Pathway Inhibitor
Epi
Lipoprotein-Associated Coagulation Inhibitor
Laci
Database Links Reactome: R-HSA-140834
Cellular Localisation Isoform Alpha: Secreted
Isoform Beta: Microsome Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Tissue Factor Pathway Inhibitor antibody
Anti-Tfpi antibody
Anti-Extrinsic Pathway Inhibitor antibody
Anti-Epi antibody
Anti-Lipoprotein-Associated Coagulation Inhibitor antibody
Anti-Laci antibody
Anti-TFPI antibody
Anti-LACI antibody
Anti-TFPI1 antibody

Information sourced from Uniprot.org

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