Anti-TFPI antibody (200-304) [S9MR] (STJ11102359)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal TFPI (200-304) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TFPI |
| Gene ID | 7035 |
| Uniprot ID | TFPI1_HUMAN |
| Immunogen Region | 200-304 |
| Immunogen Sequence | PQSTKVPSLFEFHGPSWCLT PADRGLCRANENRFYYNSVI GKCRPFKYSGCGGNENNFTS KQECLRACKKGFIQRISKGG LIKTKRKRKKQRVKIAYEEI FVKNM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 200-304 of human TFPI (P10646). |
Additional Info
| Tissue Specificity | Mostly in endothelial cells. |
| Post Translational Modifications | O-glycosylated. |
| Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
| Protein Name | Tissue Factor Pathway InhibitorTfpiExtrinsic Pathway InhibitorEpiLipoprotein-Associated Coagulation InhibitorLaci |
| Database Links | Reactome: R-HSA-140834 |
| Cellular Localisation | Isoform Alpha: SecretedIsoform Beta: Microsome MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Tissue Factor Pathway Inhibitor antibodyAnti-Tfpi antibodyAnti-Extrinsic Pathway Inhibitor antibodyAnti-Epi antibodyAnti-Lipoprotein-Associated Coagulation Inhibitor antibodyAnti-Laci antibodyAnti-TFPI antibodyAnti-LACI antibodyAnti-TFPI1 antibody |
Information sourced from Uniprot.org