Anti-TFEC antibody (N-Term) (STJ70170)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TFEC (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 40-45kDa band seen in Human Testis lysate. Recommended for use at 0.5-2µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TFEC |
| Gene ID | 22797 |
| Uniprot ID | TFEC_HUMAN |
| Accession Number | NP_036384.1; NP_001018068.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | TLDHQIINPTLK |
| Specificity | This antibody is expected to recognise both reported Human isoforms according to NP_036384.1 and NP_001018068.1. |
Additional Info
| Function | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form. |
| Protein Name | Transcription Factor EcTfe-CClass E Basic Helix-Loop-Helix Protein 34Bhlhe34Transcription Factor Ec-LikeHtfec-L |
| Database Links | Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ec antibodyAnti-Tfe-C antibodyAnti-Class E Basic Helix-Loop-Helix Protein 34 antibodyAnti-Bhlhe34 antibodyAnti-Transcription Factor Ec-Like antibodyAnti-Htfec-L antibodyAnti-TFEC antibodyAnti-BHLHE34 antibodyAnti-TCFEC antibodyAnti-TFECL antibody |
Information sourced from Uniprot.org