| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:5000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TF |
| Gene ID: |
7018 |
| Uniprot ID: |
TRFE_HUMAN |
| Immunogen Region: |
355-698 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 355-698 of human Transferrin (NP_001054.2). |
| Immunogen Sequence: |
TDECKPVKWCALSHHERLKC DEWSVNSVGKIECVSAETTE DCIAKIMNGEADAMSLDGGF VYIAGKCGLVPVLAENYNKS DNCEDTPEAGYFAIAVVKKS ASDLTWDNLKGKKSCHTAVG RTAGWNIPMGLLYNKINHCR FDEFFSEGCAPGSKKDSSLC KLCMGSGLNLCEPNNKEGYY GYTGAFRCLVEKGDVAFVKH QTVPQNTGGKNPDPWAKNLN EKDYELLCLDGTRKPVEEY |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use. |
| Protein Name | SerotransferrinTransferrinBeta-1 Metal-Binding GlobulinSiderophilin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8957275Reactome: R-HSA-917937Reactome: R-HSA-917977 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serotransferrin antibodyAnti-Transferrin antibodyAnti-Beta-1 Metal-Binding Globulin antibodyAnti-Siderophilin antibodyAnti-TF antibodyAnti-PRO1400 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
