Anti-TESPA1 antibody (STJA0009382)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TESPA1
General Information
| Short Description | Rabbit polyclonal anti-Protein TESPA1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TESPA1 |
| Gene ID | 9840 |
| Uniprot ID | TESP1_HUMAN |
| Immunogen | Synthesized peptide derived from human TESPA1 |
| Specificity | This antibody detects endogenous levels of TESPA1 at Human, Mouse |
Additional Info
| Function | Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. |
| Protein Name | Protein Tespa1Thymocyte-Expressed Positive Selection-Associated Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmEndoplasmic Reticulum MembraneMay Localize To Mitochondria-Associated Endoplasmic Reticulum Membrane (Mam) |
| Alternative Antibody Names | Anti-Protein Tespa1 antibodyAnti-Thymocyte-Expressed Positive Selection-Associated Protein 1 antibodyAnti-TESPA1 antibodyAnti-KIAA0748 antibodyAnti-HSPC257 antibody |
Information sourced from Uniprot.org