Anti-Tenascin antibody [R08-9D8] (STJA0035890)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Tenascin C
General Information
| Short Description | Rabbit monoclonal anti-Tenascin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-9D8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TNC |
| Gene ID | 3371 |
| Uniprot ID | TENA_HUMAN |
| Immunogen | A synthesized peptide derived from human Tenascin C |
Additional Info
| Tissue Specificity | Detected in fibroblasts (at protein level). |
| Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
| Protein Name | TenascinTnCytotactinGmemGp 150-225Glioma-Associated-Extracellular Matrix AntigenHexabrachionJiMyotendinous AntigenNeuronectinTenascin-CTn-C |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Tenascin antibodyAnti-Tn antibodyAnti-Cytotactin antibodyAnti-Gmem antibodyAnti-Gp 150-225 antibodyAnti-Glioma-Associated-Extracellular Matrix Antigen antibodyAnti-Hexabrachion antibodyAnti-Ji antibodyAnti-Myotendinous Antigen antibodyAnti-Neuronectin antibodyAnti-Tenascin-C antibodyAnti-Tn-C antibodyAnti-TNC antibodyAnti-HXB antibody |
Information sourced from Uniprot.org