• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using GPSN2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of 293T lysis using GPSN2 antibody. Antibody was diluted at 1:2000

Anti-TECR antibody (259-308 aa) (STJ93407)

SKU:
STJ93407

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Very-long-chain enoyl-CoA reductase (259-308 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TECR
Gene ID: 9524
Uniprot ID: TECR_HUMAN
Immunogen Region: 259-308 aa
Specificity: GPSN2 Polyclonal Antibody detects endogenous levels of GPSN2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GPSN2 at the amino acid range 259-308
Post Translational Modifications Glycosylated.
Function Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids through the sphingosine 1-phosphate metabolic pathway. Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Catalyzes the saturation step of the sphingosine 1-phosphate metabolic pathway, the conversion of trans-2-hexadecenoyl-CoA to palmitoyl-CoA.
Protein Name Very-Long-Chain Enoyl-Coa Reductase
Synaptic Glycoprotein Sc2
Trans-2 -3-Enoyl-Coa Reductase
Ter
Database Links Reactome: R-HSA-75876
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Very-Long-Chain Enoyl-Coa Reductase antibody
Anti-Synaptic Glycoprotein Sc2 antibody
Anti-Trans-2 -3-Enoyl-Coa Reductase antibody
Anti-Ter antibody
Anti-TECR antibody
Anti-GPSN2 antibody
Anti-SC2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance