Anti-TCP 1 alpha antibody [R06-8G2] (STJA0035378)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human TCP1 alpha/CCTA
General Information
| Short Description | Rabbit monoclonal anti-TCP 1 alpha for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human and Hamster samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Hamster |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-8G2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TCP1 |
| Gene ID | 6950 |
| Uniprot ID | TCPA_HUMAN |
| Immunogen | A synthetic peptide of human TCP1 alpha/CCTA |
Additional Info
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit AlphaTcp-1-AlphaCct-AlphaChaperonin Containing T-Complex Polypeptide 1 Subunit 1 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytosolCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Alpha antibodyAnti-Tcp-1-Alpha antibodyAnti-Cct-Alpha antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 1 antibodyAnti-TCP1 antibodyAnti-CCT1 antibodyAnti-CCTA antibody |
Information sourced from Uniprot.org