Anti-TCL1A antibody (Internal) (STJ71139)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TCL1A (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 16kDa band observed in lysates of cell lines Daudi and Jurkat (calculated MW of 13.5kDa according to NP_068801.1). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TCL1A |
| Gene ID | 8115 |
| Uniprot ID | TCL1A_HUMAN |
| Accession Number | NP_068801.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QLYPDGRYRSSD |
Additional Info
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Antibody Names | Anti-T-Cell Leukemia/Lymphoma Protein 1a antibodyAnti-Oncogene Tcl-1 antibodyAnti-Oncogene Tcl1 antibodyAnti-Protein P14 Tcl1 antibodyAnti-TCL1A antibodyAnti-TCL1 antibody |
Information sourced from Uniprot.org