Anti-TCL1A antibody (1-114) (STJ25797)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TCL1A (1-114) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCL1A |
| Gene ID | 8115 |
| Uniprot ID | TCL1A_HUMAN |
| Immunogen Region | 1-114 |
| Immunogen Sequence | MAECPTLGEAVTDHPDRLWA WEKFVYLDEKQHAWLPLTIE IKDRLQLRVLLRREDVVLGR PMTPTQIGPSLLPIMWQLYP DGRYRSSDSSFWRLVYHIKI DGVEDMLLELLPDD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human TCL1A (NP_001092195.1). |
Additional Info
| Tissue Specificity | Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Antibody Names | Anti-T-Cell Leukemia/Lymphoma Protein 1a antibodyAnti-Oncogene Tcl-1 antibodyAnti-Oncogene Tcl1 antibodyAnti-Protein P14 Tcl1 antibodyAnti-TCL1A antibodyAnti-TCL1 antibody |
Information sourced from Uniprot.org