Anti-TCIRG1 antibody [SRM13431] (STJ11108161)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal V-Type Proton Atpase 116 Kda Subunit A 3 antibody for use in WB, IF, ICC, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13431 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:2000-1:8000IF/ICC, 1:200-1:800IF-P, 1:200-1:800IHC-P, 1:200-1:800ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCIRG1 |
| Gene ID | 10312 |
| Uniprot ID | VPP3_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation. |
| Protein Name | V-Type Proton Atpase 116 Kda Subunit A 3V-Atpase 116 Kda Subunit A 3Osteoclastic Proton Pump 116 Kda SubunitOc-116 KdaOc116T-Cell Immune Regulator 1T-Cell Immune Response Cdna7 ProteinTirc7Vacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Proton Atpase 116 Kda Subunit A 3 antibodyAnti-V-Atpase 116 Kda Subunit A 3 antibodyAnti-Osteoclastic Proton Pump 116 Kda Subunit antibodyAnti-Oc-116 Kda antibodyAnti-Oc116 antibodyAnti-T-Cell Immune Regulator 1 antibodyAnti-T-Cell Immune Response Cdna7 Protein antibodyAnti-Tirc7 antibodyAnti-Vacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 antibodyAnti-TCIRG1 antibodyAnti-ATP6N1C antibodyAnti-ATP6V0A3 antibody |
Information sourced from Uniprot.org