Anti-TCHH antibody (STJA0009799)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Trichohyalin
General Information
| Short Description | Rabbit polyclonal anti-Trichohyalin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCHH |
| Gene ID | 7062 |
| Uniprot ID | TRHY_HUMAN |
| Immunogen | Synthesized peptide derived from human Trichohyalin |
| Specificity | This antibody detects endogenous levels of Trichohyalin at Human |
Additional Info
| Post Translational Modifications | Substrate of transglutaminase. Some 200 arginines are probably converted to citrullines by peptidylarginine deimidase. |
| Function | Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation. |
| Protein Name | Trichohyalin |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Trichohyalin antibodyAnti-TCHH antibodyAnti-THH antibodyAnti-THL antibodyAnti-TRHY antibody |
Information sourced from Uniprot.org