Anti-TCF4 antibody (Internal) (STJ71640)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TCF4 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 70kDa band observed in Human Heart lysates (calculated MW of 71.3kDa according to NP_003190.1). Recommended concentration: 0.5-1.5µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TCF4 |
| Gene ID | 6925 |
| Uniprot ID | ITF2_HUMAN |
| Accession Number | NP_001077431.1 ; NP_003190.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | NGGHPSPSRNYGDGT |
| Specificity | This antibody is expected to recognise the reported isoforms a and b (NP_001077431.1; NP_003190.1) |
Additional Info
| Function | Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'. |
| Protein Name | Transcription Factor 4Tcf-4Class B Basic Helix-Loop-Helix Protein 19Bhlhb19Immunoglobulin Transcription Factor 2Itf-2Sl3-3 Enhancer Factor 2Sef-2 |
| Database Links | Reactome: R-HSA-525793Reactome: R-HSA-9839394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor 4 antibodyAnti-Tcf-4 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 19 antibodyAnti-Bhlhb19 antibodyAnti-Immunoglobulin Transcription Factor 2 antibodyAnti-Itf-2 antibodyAnti-Sl3-3 Enhancer Factor 2 antibodyAnti-Sef-2 antibodyAnti-TCF4 antibodyAnti-BHLHB19 antibodyAnti-ITF2 antibodyAnti-SEF2 antibody |
Information sourced from Uniprot.org