Anti-TCEA1 antibody (75-140) (STJ112559)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TCEA1 (75-140) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCEA1 |
| Gene ID | 6917 |
| Uniprot ID | TCEA1_HUMAN |
| Immunogen Region | 75-140 |
| Immunogen Sequence | KLLDGPSTEKDLDEKKKEPA ITSQNSPEAREESTSSGNVS NRKDETNARDTYVSSFPRAP STSDSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 75-140 of human TCEA1 (NP_006747.1). |
Additional Info
| Function | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. |
| Protein Name | Transcription Elongation Factor A Protein 1Transcription Elongation Factor S-Ii Protein 1Transcription Elongation Factor Tfiis.o |
| Database Links | Reactome: R-HSA-112382Reactome: R-HSA-167152Reactome: R-HSA-167200Reactome: R-HSA-167238Reactome: R-HSA-167243Reactome: R-HSA-167246Reactome: R-HSA-167287Reactome: R-HSA-167290Reactome: R-HSA-674695Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6796648Reactome: R-HSA-75955 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Elongation Factor A Protein 1 antibodyAnti-Transcription Elongation Factor S-Ii Protein 1 antibodyAnti-Transcription Elongation Factor Tfiis.o antibodyAnti-TCEA1 antibodyAnti-GTF2S antibodyAnti-TFIIS antibody |
Information sourced from Uniprot.org