| Short Description : | Rabbit monoclonal anti-Thromboxane A2 receptor (300-343 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R68-6F-6 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000 |
| Formulation: | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TBXA2R |
| Gene ID: | 6915 |
| Uniprot ID: | TA2R_HUMAN |
| Immunogen: | A synthesized peptide derived from human Thromboxane A2 receptor |
| Immunogen Region: | 300-343 aa |
| Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1: Activates adenylyl cyclase. Isoform 2: Inhibits adenylyl cyclase. |
| Protein Name | Thromboxane A2 ReceptorTxa2-RProstanoid Tp Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-428930 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Thromboxane A2 Receptor antibodyAnti-Txa2-R antibodyAnti-Prostanoid Tp Receptor antibodyAnti-TBXA2R antibody |
Information sourced from Uniprot.org
