Anti-TBRG1 antibody (STJA0009042)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TBRG1
General Information
| Short Description | Rabbit polyclonal anti-Transforming growth factor beta regulator 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBRG1 |
| Gene ID | 84897 |
| Uniprot ID | TBRG1_HUMAN |
| Immunogen | Synthesized peptide derived from human TBRG1 |
| Specificity | This antibody detects endogenous levels of TBRG1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Ubiquitinated.mediated by MDM2 and leading to its subsequent proteasomal degradation. |
| Function | Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. |
| Protein Name | Transforming Growth Factor Beta Regulator 1Nuclear Interactor Of Arf And Mdm2 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transforming Growth Factor Beta Regulator 1 antibodyAnti-Nuclear Interactor Of Arf And Mdm2 antibodyAnti-TBRG1 antibodyAnti-NIAM antibody |
Information sourced from Uniprot.org