Anti-TBR1 antibody (STJ191730)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-T-box brain protein 1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBR1 |
| Gene ID | 10716 |
| Uniprot ID | TBR1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | TBR1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
| Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Brain Protein 1 antibodyAnti-T-Brain-1 antibodyAnti-Tbr-1 antibodyAnti-Tes-56 antibodyAnti-TBR1 antibody |
Information sourced from Uniprot.org