Anti-TBCK antibody (STJA0004627)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human TBCK
General Information
| Short Description | Rabbit polyclonal anti-Tbc Domain-Containing Protein Kinase-Like Protein for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.78 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:30-1:150 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TBCK |
| Gene ID | 93627 |
| Uniprot ID | TBCK_HUMAN |
| Immunogen | Synthetic peptide of human TBCK |
Additional Info
| Function | Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction. Also involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the control of actin-cytoskeleton organization. |
| Protein Name | Tbc Domain-Containing Protein Kinase-Like ProteinFerry Endosomal Rab5 Effector Complex Subunit 1Fy-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMidbodyEarly EndosomeMainly Localized In The Cytoplasm During InterphaseDuring MetaphaseTbck Accumulates At The Mitotic SpindleAt The End Of MitosisIt Is Detected At The Midbody |
| Alternative Antibody Names | Anti-Tbc Domain-Containing Protein Kinase-Like Protein antibodyAnti-Ferry Endosomal Rab5 Effector Complex Subunit 1 antibodyAnti-Fy-1 antibodyAnti-TBCK antibodyAnti-FERRY1 antibodyAnti-TBCKL antibodyAnti-HSPC302 antibody |
Information sourced from Uniprot.org