Anti-TBCB antibody (1-244aa) [AT1F6] (STJA0041689)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human TBCB (1-244aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-TBCB (1-244aa) for use in ELISA, WB, FACS, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/FACS/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1F6 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBCB |
| Gene ID | 1155 |
| Uniprot ID | TBCB_HUMAN |
| Accession Number | NP_001272 |
| Immunogen | Recombinant human TBCB (1-244aa) purified from E. coli |
| Immunogen Region | 1-244aa |
Additional Info
| Tissue Specificity | Found in most tissues. |
| Post Translational Modifications | Phosphorylation by PAK1 is required for normal function. Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome. (Microbial infection) Glycosylated residues by S.typhimurium protein Ssek1: arginine GlcNAcylation promotes microtubule stability. |
| Function | Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth. |
| Protein Name | Tubulin-Folding Cofactor BCytoskeleton-Associated Protein 1Cytoskeleton-Associated Protein CkapiTubulin-Specific Chaperone B |
| Database Links | Reactome: R-HSA-389977 |
| Cellular Localisation | CytoplasmCytoskeletonColocalizes With MicrotubulesIn Differentiated NeuronsLocated In The CytoplasmIn Differentiating NeuronsAccumulates At The Growth Cone |
| Alternative Antibody Names | Anti-Tubulin-Folding Cofactor B antibodyAnti-Cytoskeleton-Associated Protein 1 antibodyAnti-Cytoskeleton-Associated Protein Ckapi antibodyAnti-Tubulin-Specific Chaperone B antibodyAnti-TBCB antibodyAnti-CG22 antibodyAnti-CKAP1 antibody |
Information sourced from Uniprot.org